Human MYDGF mRNA Mimetic

$1,550.00$2,025.00

Myeloid-derived growth factor

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SKU: 00135-MYDGF Category:

Description

GENE NAME (BOLD) / SYNONYMS:

MYDGF / C19orf10 IL25

ENCODED PROTEIN NAME:

Myeloid-derived growth factor (UniProt: http://www.uniprot.org/uniprot/Q969H8)

Function:

Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis (PubMed:25581518).

Protein Sequence (173aa):

MAAPSGGWNGVGASLWAALLLGAVALRPAEAVSEPTTVAFDVRPGGVVHSFSHNVGPGDKYTCMFTYASQGGTNEQWQMSLGTSEDHQHFTCTIWRPQGKSYLYFTQFKAEVRGAEIEYAMAYSKAAFERESDVPLKTEEFEVTKTAVAHRPGAFKAELSKLVIVAKASRTEL

Gene Coding Sequence:

For the MYDGF DNA coding sequence will be used as the template for synthesis of the MYDGF mimetic, please send request to PhaRNA customer service: customerservice@pharna.com

Additional information

Amounts Available

0.5 mg, 1 mg