GENE NAME (BOLD) / SYNONYMS:
IL6 / IFNB2
ENCODED PROTEIN NAME:
Interleukin-6 (UniProt: http://www.uniprot.org/uniprot/P05231)
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
Protein Sequence (212aa):
Gene Coding Sequence:
For the IL6 DNA coding sequence will be used as the template for synthesis of the IL6 mimetic, please send request to PhaRNA customer service: firstname.lastname@example.org a> em>