Human IL26 mRNA Mimetic

$1,550.00$2,025.00

Interleukin-26

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SKU: 00136-IL26 Category:

Description

GENE NAME (BOLD) / SYNONYMS:

IL26 / AK155

ENCODED PROTEIN NAME:

Interleukin-26 (UniProt: http://www.uniprot.org/uniprot/Q9NPH9)

Function:

May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.

Protein Sequence (171aa):

MLVNFILRCGLLLVTLSLAIAKHKQSSFTKSCYPRGTLSQAVDALYIKAAWLKATIPEDRIKNIRLLKKKTKKQFMKNCQFQEQLLSFFMEDVFGQLQLQGCKKIRFVEDFHSLRQKLSHCISCASSAREMKSITRMKRIFYRIGNKGIYKAISELDILLSWIKKLLESSQ

Gene Coding Sequence:

For the IL26 DNA coding sequence will be used as the template for synthesis of the IL26 mimetic, please send request to PhaRNA customer service: customerservice@pharna.com

Additional information

Amounts Available

0.5 mg, 1 mg