GENE NAME (BOLD) / SYNONYMS:
IL1B / IL1F2
ENCODED PROTEIN NAME:
Interleukin-1 beta (UniProt: http://www.uniprot.org/uniprot/P01584)
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.
Protein Sequence (269aa):
Gene Coding Sequence:
For the IL1B DNA coding sequence will be used as the template for synthesis of the IL1B mimetic, please send request to PhaRNA customer service: firstname.lastname@example.org a> em>