Human IL1A mRNA Mimetic

$1,550.00$2,025.00

Interleukin-1 alpha

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SKU: 00110-IL1A Category:

Description

GENE NAME (BOLD) / SYNONYMS:

IL1A / IL1F1

ENCODED PROTEIN NAME:

Interleukin-1 alpha (UniProt: http://www.uniprot.org/uniprot/P01583)

Function:

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Protein Sequence (271aa):

MAKVPDMFEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISETSKTSKLTFKESMVVVATNGKVLKKRRLSLSQSITDDDLEAIANDSEEEIIKPRSAPFSFLSNVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHPNLFIATKQDYWVCLAGGPPSITDFQILENQA

Gene Coding Sequence:

For the IL1A DNA coding sequence will be used as the template for synthesis of the IL1A mimetic, please send request to PhaRNA customer service: customerservice@pharna.com

Additional information

Amounts Available

0.5 mg, 1 mg