GENE NAME (BOLD) / SYNONYMS:
IL1A / IL1F1
ENCODED PROTEIN NAME:
Interleukin-1 alpha (UniProt: http://www.uniprot.org/uniprot/P01583)
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Protein Sequence (271aa):
Gene Coding Sequence:
For the IL1A DNA coding sequence will be used as the template for synthesis of the IL1A mimetic, please send request to PhaRNA customer service: firstname.lastname@example.org a> em>