GENE NAME (BOLD) / SYNONYMS:
CXCL8 / IL8
ENCODED PROTEIN NAME:
Interleukin-8 (UniProt: http://www.uniprot.org/uniprot/P10145)
IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
Protein Sequence (99aa):
Gene Coding Sequence:
For the CXCL8 DNA coding sequence will be used as the template for synthesis of the CXCL8 mimetic, please send request to PhaRNA customer service: firstname.lastname@example.org a> em>