Human CXCL8 mRNA Mimetic

$1,550.00$2,025.00

Interleukin-8

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SKU: 00118-CXCL8 Category:

Description

GENE NAME (BOLD) / SYNONYMS:

CXCL8 / IL8

ENCODED PROTEIN NAME:

Interleukin-8 (UniProt: http://www.uniprot.org/uniprot/P10145)

Function:

IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.

Protein Sequence (99aa):

MTSKLAVALLAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS

Gene Coding Sequence:

For the CXCL8 DNA coding sequence will be used as the template for synthesis of the CXCL8 mimetic, please send request to PhaRNA customer service: customerservice@pharna.com

Additional information

Amounts Available

0.5 mg, 1 mg