Several studies indicate that cannabis interacts with opioids and alters the associated pain-relieving effects. When co-administered, patients can use a lower dose of opioids and achieve the same level of pain relief, thereby reducing the risk of side effects and addiction.

In legalized medical cannabis states, substituting opioids with cannabis and decreasing opioid overdose deaths have already been observed. Cannabis can be used to wean patients off their current opioid regimen and provide pain relief that is comparable to opioid treatment. There is the potential to fight addiction with CBD, reducing drug cravings and symptoms of withdrawal.  More research is needed to identify specific treatment plans for pain relief and drug addiction, but it’s possible that a mixture of THC and CBD could be an effective medication against chronic pain and opioid drug dependence.